Differentiate between osteoarthritis and rheumatoid arthritis. How does the pathophysiology of the diseases differ?

Renal and Musculoskeletal Modifications | Nursing homework help

Two types of arthritis are osteoarthritis (OA), and rheumatoid (RA). OA is a degenerative joint disease that is caused by wear and tear on the joints due to overuse or aging, while RA is an autoimmune disorder in which the body’s immune system mistakenly attacks its own joint tissues.

These two diseases have different pathophysiologies. OA only affects certain areas of the joint like the cartilage while RA can affect multiple parts such as synovial membranes, tendons and ligaments, bone tissue, and even the bones. OA causes gradual joint deterioration over time, while RA can lead to inflammation that leads to pain and swelling in a matter days or weeks. OA is not associated with fever or fatigue, but RA could cause extra-articular symptoms, such as rash or eye irritation.

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