Describe the disease, its prevalence, its incidence and general knowledge of the disease. Discuss the laboratory testing that can be done.

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Lupus is an autoimmune illness that impacts 1.5 million folks in the US, with girls being extra prone to be identified than males. It’s characterised by irritation and harm to varied organs all through the physique which may result in a variety of signs together with fatigue, joint ache and pores and skin rashes. Analysis relies on a mix of scientific presentation in addition to laboratory testing.

The most typical laboratory assessments used for diagnosing lupus are antinuclear antibody (ANA) take a look at, anti-double stranded DNA (dsDNA) take a look at and complement ranges. ANA testing appears to be like for autoantibodies that focus on parts of the affected person’s personal cells whereas dsDNA assessments detect antibodies directed in opposition to double stranded DNA molecules related to systemic lupus erythematosus (SLE). Complement ranges are additionally useful in confirming analysis since they supply details about any deficiencies or abnormalities current within the affected person’s immune system.

General, these assessments assist decide if signs skilled by the affected person are as a result of lupus or different situations whereas ruling out potential causes resembling infections or drug reactions. In addition they assist inform prognosis in order that applicable remedy plans could be developed with a purpose to handle signs and cut back recurrence of flare ups.

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